Relationship between granulomatous lobular mastitis and methylene tetrahydrofolate reductase gene polymorphism
نویسندگان
چکیده
منابع مشابه
Granulomatous lobular mastitis
Granulomatous lobular mastitis is an unusual breast benign inflammatory disorder with unknown aetiology. It is generally emerged with the clinical symptoms of breast mass, abscess, inflammation and mammary duct fistula. The diagnosis is made by histopathology with a chronic non-necrotizing granulomatous inflammation in lobules of the breast tissue as the microscopic feature. Therapy of granulom...
متن کاملGranulomatous mastitis including breast tuberculosis and idiopathic lobular granulomatous mastitis.
titis (ILGM) is a rare chronic inflammatory disease of the breast that can clinically mimic breast carcinoma. Patients usually present with progressive onset of a breast lump. The most common clinical presentation is a firm unilateral, discrete breast mass, often associated with an inflammation of the overlying skin. Nipple retraction and even a sinus formation are present. Regional lymphadenop...
متن کاملPrevalence of methylene tetrahydrofolate reductase polymorphism in South Indian population
Prevalence of methylene tetrahydrofolate reductase (MTHFR) gene mutations in South Indian population was investigated from a total of 608 samples, 420 adults and 188 newborns. Detection of mutation was carried out focussing on the two most common mutations of the MTHFR gene (C677T and A1298C) using PCRbased RFLP method. T-allele frequency was almost similar between the newborns and adults (0.09...
متن کاملReview Article Methylene Tetrahydrofolate Reductase Gene and Coronary Artery Disease
Hyperhomocysteinemia has been identified as a risk factor for coronary artery disease (CAD).1-9 In a nested case control study in Norway on 21,826 subjects in general population, hyperhomocysteinemia was clearly identified as an independent risk factor for CAD with no threshold level.9 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the methylation of homocysteine and its role in...
متن کامل[Mutations in the methylene-tetrahydrofolate reductase gene and Down syndrome].
Down syndrome (DS) is a complex genetic and metabolic disorder attributed to the presence of three copies of chromosome 21. The extra chromosome derives from the mother in 93% of cases and is due to abnormal chromosome segregation during meiosis (nondisjunction). Except for advanced age at conception, maternal risk factors for meiotic nondisjunction are not well established. A recent preliminar...
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ژورنال
عنوان ژورنال: World Journal of Clinical Cases
سال: 2020
ISSN: 2307-8960
DOI: 10.12998/wjcc.v8.i18.4017